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Bisolvon Muco 10 comprimidos efervescentes View larger

Bisolvon Muco 10 comprimidos efervescentes

Indicated in catarrhal and flu-like processes: 1 tablet a day reduces the viscosity of mucus favoring their elimination

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6,10 € tax incl.

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 Each tablet contains 600 mg of acetylcysteine

 It reduces the viscosity of bronchial secretions, promoting their elimination.

- Bronchial hyperviscosity.
* Reduces the viscosity of bronchial mucus in colds, common cold and flu.

- Adults, oral: 600 mg / 24 h in a single dose, preferably in the morning, and with food.
- Children and adolescents under 18 years old, oral: has not been evaluated for safety and effectiveness.
Forgotten dose: take as soon as possible if little time has elapsed. Otherwise, skip the dose. Do not double the dose in the next administration.
Duration of treatment if symptoms do not improve or worsen after 5 days of treatment, or is accompanied by fever, rash, headache or persistent sore throat, consult your doctor and / or pharmacist.
It is recommended that acetylcysteine ​​with food. If a single dose administration, is best done in the morning.
Forgotten dose: take as soon as possible if little time has elapsed. Otherwise, skip the dose. Do not double the dose in the next administration.

Dissolve effervescent tablets or the contents of the envelopes in a glass of water, drinking once effervescence has stopped.

- Hypersensitivity to any component of the medication.

- This product contains lactose. Patients with hereditary intolerance to lactose or galactose, Lapp lactase deficiency or glucose-galactose malabsorption should not take this medicine.
- This medicine contains sorbitol. Patients with hereditary fructose intolerance should not take this medicine.
- This medicine contains sodium. For the exact content of sodium, it is recommended to review the composition. Oral and parenteral dosage forms with amounts of sodium than 1 mmol (23 mg) / maximum daily dose should be used with caution in patients with or with sodium diet.

- Severe liver failure, liver cirrhosis. In these patients, the clearance may be decreased, resulting in increased risk of adverse reactions, so it is recommended to closely monitor the patient to the risk of adverse reactions anaphylactic.
- Ulcer Petica. Acetylcysteine ​​sometimes can lead to nausea and vomiting, especially at high doses, and therefore there was an increased risk of gastric bleeding. Furthermore, it has also been postulated that acetylcysteine ​​result in increased fluidity gastric mucus, resulting in a decrease of the protective action thereof. It is recommended caution in patients with peptic ulcer.
- Asthma. In asthmatic patients with severe respiratory failure or those with diseases associated with bronchial spasm, increased fluidity of secretions may lead to obstruction of the airway if the expectoration is not adequate. It is recommended therefore exercise caution.
- Increased expectoration. At the beginning of treatment, you may see an increase in expectoration, due to increased fluidity of secretions. This effect decreases after several days of treatment. If symptoms persist or worsen after five days of treatment, it is advised to reevaluate the clinical situation.

- It is recommended to drink plenty of water during treatment.
- The preparation may have a slight sulfurous, characteristic of the active ingredient and not an alteration of the preparation odor.
- It should be noted doctor if a generalized itching appears by the body.
- If after five days, the symptoms continue or worsen, it is advisable to see a doctor.

- Antibiotics. Acetylcysteine ​​could be incompatible with amphotericin B, ampicillin sodium, cephalosporins, erythromycin lactobionate or some tetracyclines. It is recommended to separate the take at least an interval of two hours.
- Antitussives. Acetylcysteine ​​increases the fluidity of bronchial secretions, so it is not advisable to administer along with antitussives, which could inhibit the cough reflex and lead to pulmonary obstruction.
- Inhibitor medicines bronchial secretion (anticholinergics, tricyclic antidepressants, H1 antihistamines, anti-Parkinson, MAO inhibitors, neuroleptics). They can antagonize the effects of acetylcysteine.
- Nitroglycerin. Acetylcysteine ​​may potentiate the vasodilatory effects of nitroglycerin and adverse to very high doses (100 mg / kg) reactions.
- Metal salts. Acetylcysteine ​​could present certain chelating effects of some metals such as gold, calcium or iron, which would reduce its absorption. It is recommended distance making mineral supplements and acetylcysteine ​​at least two hours.

Category B FDA. Administration of 500 mg / kg / 24 hours orally or nebulization acetylcysteine ​​and isoproterenol for 30-35 minutes in pregnant rabbits showed no teratogenicity. The peri and post-natal studies also failed to find evidence of fetal harm or the newborn. Acetylcysteine ​​appears to cross the placental barrier. There have been no adequate and well-controlled studies in humans, so the use of this medicine only accepted if no safer therapeutic alternatives.

It is unknown whether acetylcysteine ​​is excreted in milk, and if this could affect the child. It is recommended to stop breastfeeding or prevent the administration of this medicine.

This medicine is contraindicated in children under 2 years old and is not suitable for use in children and adolescents.

No specific problems have been reported in this age group. However, in these patients it is usually more common the presence of hepatic or respiratory failure, so it is recommended to be used with caution acetylcysteine.

Acetylcysteine ​​does not usually lead to phenomena of sleepiness, but exceptionally described some cases. Caution is advised when driving, to be the relative certainty that the treatment does not adversely affect the patient's ability.

Adverse reactions of acetylcysteine ​​are rare, mild and transient. The most common adverse reactions are:
- Digestive. Sometimes nausea, vomiting, diarrhea and gastric hyperacidity, especially when used at high doses may appear.
- Liver. There have been some cases of increased transaminases after administration of large doses of acetylcysteine, which reversed after a few days of stopping treatment.
- Neurologic / psychological. There have been some cases of headache and drowsiness.
- Respiratory Tract. Usually exclusive administration by inhalation. rhinorrhea, bronchitis, tracheitis, hemoptysis and bronchospasm may occur.
- Eyepieces. Blurry vision.
- Disorders Ear and labyrinth, ototoxicity: tinnitus.
- Allergic / Dermatological. After 30-60 minutes of administration, hypersensitivity reactions that occur with generalized urticaria, mild fever, itching, rash rash, angioedema, dyspnoea and hypotension may occur. These reactions are more frequent and severe in the case of parenteral administration, can be fatal, while oral or inhalation is rare to occur.
In case of allergic reactions, it is recommended to temporarily discontinue treatment and administer antihistamines H1, and if necessary, adrenaline. If the allergic reaction is repeated, it should be withdrawn and not start again.
- General. Excessive sweating.

Symptoms: Acetylcysteine ​​has been administered in man at doses up to 500 mg / kg / 24 hours without causing side effects, so it is possible to exclude the possibility of poisoning by overdose of this active ingredient. However, in case of massive ingestion, the appearance of an intensification of the adverse effects are expected, mainly gastrointestinal.
Treatment: resort to symptomatic treatment. the airway clear of secretions, resting the patient and keep practicing bronchial aspiration. If deemed necessary, and have no more than 30 minutes after ingestion, gastric lavage is performed.



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Bisolvon Muco 10 comprimidos efervescentes

Bisolvon Muco 10 comprimidos efervescentes

Indicated in catarrhal and flu-like processes: 1 tablet a day reduces the viscosity of mucus favoring their elimination

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